SCHEMBL19783853

SCHEMBL19783853

O=c1cnn(-c2ccc3nn(-c4cncc(F)c4)cc3c2)c(=O)n1S

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.37
ESR2 Q92731 1/20 0.31
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21422276 0.87 CYP11B2 (0.37) CYP11B2ESR2SCN9A
SCHEMBL19784144 0.85 CYP11B2 (0.34) CYP11B2
SCHEMBL22172083 0.84 CYP11B2 (0.36) CYP11B2
SCHEMBL19783854 0.84 TLR8 (0.38) CYP11B2ESR2
SCHEMBL19783971 0.83 CYP11B2 (0.39) CYP11B2
SCHEMBL22172067 0.79 ESR2 (0.31) CYP11B2ESR2
SCHEMBL21422260 0.72 CYP11B2 (0.34) CYP11B2
SCHEMBL19784106 0.72 TLR8 (0.38) CYP11B2ESR2
SCHEMBL21422278 0.72 CYP11B2 (0.36) CYP11B2
SCHEMBL31457236 0.71 ESR2 (0.39) CYP11B2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484877-B1 BICYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2020-07-01 EP disclosed
WO-2018011111-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-18 WO disclosed