Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220029 | 0.87 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1642202 | 0.87 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19783899 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28295623 | 0.85 | MEN1 (0.51) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3651432 | 0.81 | MEN1 (0.56) | MEN1KMT2APTGESNPC1RAB9A | |
| SCHEMBL20969294 | 0.81 | MEN1 (0.56) | MEN1KMT2APTGESNPC1RAB9A | |
| SCHEMBL12492396 | 0.77 | KMT2A (0.56) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5655931 | 0.77 | KMT2A (0.56) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5655937 | 0.77 | KMT2A (0.56) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8472602 | 0.77 | KMT2A (0.49) | MEN1KMT2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011017-A1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |