Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651432 | 1.00 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL28295623 | 0.85 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL8476480 | 0.83 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL8477591 | 0.83 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL7149533 | 0.82 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL5146172 | 0.82 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL5271778 | 0.82 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL21220029 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1642202 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19783897 | 0.81 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481823-A1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2019-05-15 | — | — | EP | disclosed |