Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783919 | 1.00 | ULK1 (0.33) | ULK1ULK2MKNK2STK17ACHRM4 | |
| SCHEMBL21220094 | 1.00 | ULK1 (0.33) | ULK1ULK2MKNK2STK17ACHRM4 | |
| SCHEMBL21220070 | 0.93 | ULK1 (0.34) | ULK1ULK2MKNK2STK17AJAK2 | |
| SCHEMBL19783950 | 0.93 | ULK1 (0.34) | ULK1ULK2MKNK2STK17AJAK2 | |
| SCHEMBL19783951 | 0.93 | ULK1 (0.34) | ULK1ULK2MKNK2STK17AJAK2 | |
| SCHEMBL19783532 | 0.93 | ULK1 (0.34) | ULK1ULK2MKNK2STK17AJAK2 | |
| SCHEMBL20531857 | 0.90 | P2RX7 (0.33) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL22331782 | 0.90 | P2RX7 (0.33) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18312997 | 0.90 | P2RX7 (0.33) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL21220083 | 0.89 | P2RX7 (0.35) | P2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481823-B1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | Bayer Pharma AG (DE) | 2020-10-28 | — | — | EP | disclosed |
| WO-2018011017-A1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |