Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.86 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25175631 | 1.00 | HSD17B10 (0.86) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL2212719 | 0.98 | HSD17B10 (0.89) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL82223 | 0.93 | HSD17B10 (1.00) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL9671779 | 0.87 | MAPT (0.83) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL3814880 | 0.87 | MAPT (0.83) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL17457887 | 0.87 | HSD17B10 (0.74) | HSD17B10MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL8558008 | 0.85 | LMNA (0.69) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL11569566 | 0.85 | MAPT (0.69) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL12834782 | 0.85 | MAPT (0.69) | HSD17B10RXFP1MAPTHDAC3MAPK1 | |
| SCHEMBL6786019 | 0.85 | HSD17B10 (0.79) | HSD17B10KMT2ALMNAMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018010932-A1 | CATALYTIC CARBOXYLATION OF ACTIVATED ALKANES AND/OR OLEFINS | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ES) | 2018-01-18 | — | — | WO | disclosed |