Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82223 | 0.88 | HSD17B10 (1.00) | HSD17B10FFAR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL2212719 | 0.86 | HSD17B10 (0.89) | HSD17B10FFAR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL4623244 | 0.85 | HSD17B10 (0.63) | HSD17B10KMT2ALMNAL3MBTL1MMP12 | |
| SCHEMBL25175631 | 0.85 | HSD17B10 (0.86) | HSD17B10KMT2ALMNAL3MBTL1MMP12 | |
| SCHEMBL19784149 | 0.85 | HSD17B10 (0.86) | HSD17B10KMT2ALMNAL3MBTL1MMP12 | |
| SCHEMBL9818052 | 0.84 | KMT2A (0.73) | HSD17B10KMT2ALMNAL3MBTL1MMP12 | |
| SCHEMBL69746 | 0.84 | FFAR1 (0.81) | FFAR1KEAP1LMNAL3MBTL1FFAR4 | |
| SCHEMBL10415943 | 0.84 | FFAR1 (0.58) | HSD17B10FFAR1KEAP1LMNAL3MBTL1 | |
| SCHEMBL6471357 | 0.84 | HSD17B10 (0.62) | HSD17B10FFAR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL264975 | 0.83 | FFAR1 (0.65) | HSD17B10FFAR1KEAP1L3MBTL1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-115403459-A | Preparation method of 1, 4-dicarbonyl compound | 广州自远生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| US-6818780-B2 | APPLICATION IN MEDICINE FOR TREATMENT OF DISORDERS OF IMMUNOLOGICAL SYSTEM | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2004-11-16 | — | — | US | disclosed |
| EP-1284263-B1 | DERIVATIVES OF P- HYDROXY PHENYL PROPIONIC ACID AS ANTIPROLIFERATIVE AGENTS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2003-12-10 | — | — | EP | disclosed |
| US-20030199575-A1 | P-hydroxyphenyl propionic acid derivatives as antiproliferative agents | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-10-23 | — | — | US | disclosed |
| EP-1284263-A1 | DERIVATIVES OF P- HYDROXY PHENYL PROPIONIC ACID AS ANTIPROLIFERATIVE AGENTS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-02-19 | — | — | EP | disclosed |
| WO-2002102301-A2 | SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-12-27 | — | — | WO | disclosed |
| US-6380218-B1 | FOR THERAPY OF RESPIRATORY, ALLERGIC, AND INFLAMMATORY DISORDERS COMPRISING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ACUTE RESPIRATORY DISEASE SYNDROME, PULMONARY HYPERSENSITIVITY, AND ALLERGIC RHINITIS IN A MAMMAL | PFIZER INC | 2002-04-30 | — | — | US | disclosed |
| EP-0971894-A1 | NICOTINAMIDE DERIVATIVES | Pfizer Products Inc. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045268-A1 | NICOTINAMIDE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-10-15 | — | — | WO | disclosed |
| US-4559221-A | COMBINED WITH PHYSIOLOGICALLY ACTIVE COMPONENT AND LABELLED WITH TECHNETIUM; BLOOD CIRCULATION, CANCER DETECTION | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1985-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199575-A1 | P-hydroxyphenyl propionic acid derivatives as antiproliferative agents | P4HA1, PAH, VHL | HSD17B10 755/4885FFAR1 1492/4885KMT2A 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.