Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17374218 | 0.85 | MMP2 (0.40) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17374221 | 0.85 | MMP2 (0.40) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22420091 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28012892 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20832644 | 0.81 | MMP2 (0.49) | MAPTALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL22227868 | 0.81 | MMP2 (0.49) | MAPTALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL4221 | 0.80 | — | — | |
| SCHEMBL8891623 | 0.80 | MAPT (0.60) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2375356 | 0.80 | MAPT (0.60) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL237380 | 0.80 | MAPT (0.60) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011823-A1 | SALT OF AMINE-PROTECTED (1S,2R,4S)-1,2-AMINO-N,N-DIMETHYLCYCLOHEXANE-4-CARBOXAMIDE | MYLAN LABORATORIES LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |