SCHEMBL19784439

SCHEMBL19784439

CCOC(=O)CCCCCN(OCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.69
ALOX5 P09917 1/20 0.46
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
LTA4H P09960 2/20 0.43
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9781838 0.95 L3MBTL1 (0.65) L3MBTL1ALOX5SMN1; SMN2LTA4HCYP4F2
SCHEMBL9781776 0.86 L3MBTL1 (0.78) L3MBTL1
SCHEMBL8899583 0.85 L3MBTL1 (0.76) L3MBTL1
SCHEMBL9434778 0.83 L3MBTL1 (0.78) L3MBTL1
SCHEMBL9434959 0.83 L3MBTL1 (0.78) L3MBTL1
SCHEMBL6629239 0.83 L3MBTL1 (0.73) L3MBTL1
SCHEMBL8863680 0.82 L3MBTL1 (0.76) L3MBTL1
SCHEMBL6441659 0.82 L3MBTL1 (0.62) L3MBTL1ALOX5TDP1LTA4H
SCHEMBL9326780 0.81 L3MBTL1 (0.64) L3MBTL1
SCHEMBL9327971 0.81 L3MBTL1 (0.64) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369848-A1 Conjugation Method for Carrier-Linked Prodrugs Ascendls Pharma A/S (DK) 2021-12-02 US disclosed
WO-2018011266-A1 CONJUGATION METHOD FOR CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369848-A1 Conjugation Method for Carrier-Linked Prodrugs UGT2B7, SLC10A1, UGT1A6 L3MBTL1 2842/4885ALOX5 893/4885ALDH1A1 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.