SCHEMBL19784520

SCHEMBL19784520

c1ccc(-c2nc3ccccc3nc2-n2c3ccccc3c3c4sc5c6ccccc6ccc5c4c4ccccc4c32)cc1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.34
CASP1 P29466 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
GSR P00390 1/20 0.31
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.30
PDE10A Q9Y233 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19544164 0.93 HSD17B10 (0.35) HSD17B10CASP1HRH4CYP1A1CYP1B1
SCHEMBL19544160 0.91 HSD17B10 (0.34) HSD17B10CASP1HRH4CYP1A1CYP1B1
SCHEMBL19784826 0.87 HSD17B10 (0.36) HSD17B10CASP1HRH4KDM4EALDH1A1
SCHEMBL19544161 0.86 CYP1A1 (0.37) HSD17B10CASP1HRH4CYP1A1CYP1B1
SCHEMBL21709121 0.85 CASP1 (0.34) HSD17B10CASP1HRH4CYP1A1CYP1B1
SCHEMBL19784523 0.85 CYP1A1 (0.32) CYP1A1CYP1B1
SCHEMBL19784604 0.85 CYP1A1 (0.35) CYP1A1CYP1B1
SCHEMBL21707369 0.84 HSD17B10 (0.36) HSD17B10CASP1HRH4CYP1A1CYP1B1
SCHEMBL19544162 0.83 TUBB4A (0.32) CYP1A1CYP1B1GSR
SCHEMBL19543827 0.83 CYP1A1 (0.33) CYP1A1CYP1B1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190229271-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRONIC ELEMENT DUK SAN NEOLUX CO., LTD. (KR) 2019-07-25 US disclosed
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed