SCHEMBL19784811

SCHEMBL19784811

c1ccc(-n2c3ccc(-c4ccc5[nH]c6ccc7oc8c9ccccc9ccc8c7c6c5c4)cc3c3c4ccccc4ccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.39
CCND1 P24385 4/20 0.39
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
CYP1A1 P04798 8/20 0.32
CYP1A2 P05177 7/20 0.32
CYP1B1 Q16678 7/20 0.32
ABCG2 Q9UNQ0 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32
PRKDC P78527 2/20 0.32
PAX8 Q06710 2/20 0.32
PDE5A O76074 1/20 0.32
TP53 P04637 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784898 0.95 CDK4 (0.39) CDK4CCND1SIRT2SIRT1CYP1A1
SCHEMBL19831783 0.87 CDK4 (0.34) CDK4CCND1SIRT2SIRT1CYP1A1
SCHEMBL31624124 0.86 CDK4 (0.51) CDK4CCND1KDM4EALDH1A1HPGD
SCHEMBL14979526 0.86 CDK4 (0.51) CDK4CCND1KDM4EALDH1A1HPGD
SCHEMBL17753307 0.82 CDK4 (0.49) CDK4CCND1KDM4EALDH1A1HPGD
SCHEMBL16836872 0.82 CDK4 (0.42) CDK4CCND1KDM4EALDH1A1MAPT
SCHEMBL14979601 0.80 CDK4 (0.51) CDK4CCND1KDM4EALDH1A1HPGD
SCHEMBL22260496 0.79 KDM4E (0.40) SIRT2SIRT1CYP1A1CYP1A2CYP1B1
SCHEMBL18088948 0.78 L3MBTL1 (0.48) SIRT2SIRT1CYP1A1CYP1A2CYP1B1
SCHEMBL15073878 0.77 CDK4 (0.50) CDK4CCND1KDM4EHPGDJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-27 US disclosed
US-20190229271-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRONIC ELEMENT DUK SAN NEOLUX CO., LTD. (KR) 2019-07-25 US disclosed
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF ESR1, GPX1, LEF1 CDK4 1100/4885CCND1 835/4885SIRT2 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.