SCHEMBL19784817

SCHEMBL19784817

c1ccc(C(c2ccccc2)c2ccc(-c3ccc(-c4ccc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CRHBP P24387 1/20 0.39
ATM Q13315 1/20 0.39
CRHR2 Q13324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17069762 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL13422139 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL12211309 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL1106642 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL13170726 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL2704141 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL17167474 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL13057975 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL12888129 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4L3MBTL1MAPTTDP1
SCHEMBL17885889 0.98 CHRNB2 (0.45) ALDH1A1CYP3A4L3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018021737-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-02-01 WO disclosed
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed