SCHEMBL19784911

SCHEMBL19784911

Brc1ccc(-c2ccc(C(Cc3ccccc3)c3ccc4c(ccc5ccccc54)c3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.39
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
KCNH2 Q12809 1/20 0.38
AKR1B1 P15121 1/20 0.37
HTR2A P28223 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
THRB P10828 1/20 0.37
CYP1B1 Q16678 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
MMP2 P08253 2/20 0.36
MMP1 P03956 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18481633 0.84 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6
SCHEMBL19660512 0.78 MMP2 (0.35) ACP3CYP2D6ALDH1A1MAPK1MEN1
SCHEMBL19832034 0.77 ALDH1A1 (0.58) ACP3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL13085421 0.77 CYP2A6 (0.38) ACP3SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL29407540 0.76 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ARXFP1
SCHEMBL1527448 0.76 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ARXFP1
SCHEMBL22688319 0.71 CYP1A1 (0.40) ACP3CYP1B1CYP1A1CYP1A2
SCHEMBL30466637 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1CYP1B1CYP1A1CYP1A2
SCHEMBL1527418 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1CYP1B1CYP1A1CYP1A2
SCHEMBL2308079 0.70 AKR1B1 (0.48) SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed