SCHEMBL19785010

SCHEMBL19785010

C[Si](C)(C)c1ccc(-c2ccc(Nc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 4/20 0.48
ALOX12 P18054 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALOX15 P16050 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 2/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
EPHX2 P34913 1/20 0.46
HPGD P15428 2/20 0.45
PTGER4 P35408 1/20 0.41
CYP3A4 P08684 2/20 0.41
LMNA P02545 2/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL761318 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL762138 0.89 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL9003887 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10L3MBTL1ALOX15TDP1
SCHEMBL18271560 0.87 ALDH1A1 (0.51) ALDH1A1HSD17B10EPHX2HPGDPTGER4
SCHEMBL24203535 0.86 ESR1 (0.50) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL2270398 0.84 ALDH1A1 (0.43) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL68489 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL428698 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL21514977 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL5370467 0.82 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022222737-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE COMPRISING SAME 陕西莱特迈思光电材料有限公司 2022-10-27 WO disclosed
US-10629830-B2 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-21 US disclosed
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE ARL1, RIF1, LARS1 ALDH1A1 531/4885HSD17B10 2081/4885ALOX12 1626/4885
US-10629830-B2 Organic electroluminescent device ARL1, RIF1, LARS1 ALDH1A1 531/4885HSD17B10 2081/4885ALOX12 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.