SCHEMBL762138

SCHEMBL762138

C[Si](C)(C)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.62
HSD17B10 Q99714 6/20 0.62
ALOX12 P18054 5/20 0.62
L3MBTL1 Q9Y468 4/20 0.62
TDP1 Q9NUW8 4/20 0.62
TSHR P16473 4/20 0.62
ALOX15 P16050 3/20 0.62
MAPK1 P28482 2/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
HPGD P15428 3/20 0.56
MAPT P10636 9/20 0.50
CYP3A4 P08684 5/20 0.50
HTT P42858 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270398 0.90 ALDH1A1 (0.43) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL761318 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL19785010 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL24203518 0.84 ALDH1A1 (0.59) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL916183 0.81 HPGD (0.56) ALDH1A1L3MBTL1TDP1MAPK1HPGD
SCHEMBL760855 0.80 ALDH1A1 (0.66) ALDH1A1HSD17B10L3MBTL1ALOX15MAPK1
SCHEMBL20636767 0.79 KCNH3 (0.43) ALDH1A1ALOX12TDP1MAPK1MAPT
SCHEMBL7896372 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL9480038 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1
SCHEMBL13663470 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12495717-B2 Amine compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2025-12-09 US disclosed
US-12268086-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-04-01 US disclosed
CN-112534593-B Organic light emitting diode 株式会社LG化学 2025-01-10 CN disclosed
US-12010915-B2 Organic light-emitting diode having long lifespan, low voltage, and high efficiency property SFC CO., LTD. (KR) 2024-06-11 US disclosed
US-12006335-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2024-06-11 US disclosed
US-11980088-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-07 US disclosed
CN-113727985-B Compound and organic light emitting device comprising the same 株式会社LG化学 2024-04-16 CN disclosed
CN-113039189-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2023-12-26 CN disclosed
CN-110785405-B Compound and organic light-emitting element comprising same 株式会社LG化学 2023-12-15 CN disclosed
CN-111868028-B Amine compound and organic light emitting device comprising the same 株式会社LG化学 2023-12-08 CN disclosed
US-7919196-B2 Emitting materials and organic light emitting device using the same LG CHEM, LTD. (KR) 2011-04-05 US disclosed
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-07-29 US disclosed
CN-101735638-A Dye for dye-sensitized solar cell and solar cell including the same LG DISPLAY CO LTD 2010-06-16 CN disclosed
US-20100126563-A1 Dyes for dye sensitized solar cell LG DISPLAY CO., LTD. (KR) 2010-05-27 US disclosed
US-20100126563-A1 Dyes for dye sensitized solar cell LG DISPLAY CO., LTD. (KR) 2010-05-27 US disclosed
US-20100126563-A1 Dyes for dye sensitized solar cell LG DISPLAY CO., LTD. (KR) 2010-05-27 US disclosed
US-20100044681-A1 Novel Anthracene Derivatives, Method for Preparation Thereof, and Organic Electronic Device Using the Same LG CHEM, LTD. (KR) 2010-02-25 US disclosed
US-20090134781-A1 Diamine Derivatives, Preparation Method Thereof and Organic Electronic Device Using the Same LG CHEM, LTD. (KR) 2009-05-28 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12495717-B2 Amine compound and organic light emitting diode comprising same DRD1, RNF10, DRD2 ALDH1A1 216/4885HSD17B10 1165/4885ALOX12 76/4885
US-12268086-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 ALDH1A1 493/4885HSD17B10 2748/4885ALOX12 454/4885
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same CRY1, CRY2, PER2 ALDH1A1 112/4885HSD17B10 3250/4885ALOX12 256/4885
US-12006335-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, CYBA ALDH1A1 76/4885HSD17B10 1635/4885ALOX12 243/4885
US-20090134781-A1 Diamine Derivatives, Preparation Method Thereof and Organic Electronic Device Using the Same DDT, AOC1, DDC ALDH1A1 403/4885HSD17B10 3544/4885ALOX12 1958/4885
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME DDT, AOC1, DDC ALDH1A1 396/4885HSD17B10 2808/4885ALOX12 1824/4885
US-20100126563-A1 Dyes for dye sensitized solar cell TYR, XPA, PAH ALDH1A1 662/4885HSD17B10 2420/4885ALOX12 1412/4885
US-20100044681-A1 Novel Anthracene Derivatives, Method for Preparation Thereof, and Organic Electronic Device Using the Same XPOT, TOMM22, TIMM10 ALDH1A1 747/4885HSD17B10 676/4885ALOX12 253/4885
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT ALDH1A1 434/4885HSD17B10 1129/4885ALOX12 236/4885
US-12010915-B2 Organic light-emitting diode having long lifespan, low voltage, and high efficiency property CYBA, CRY2, AOC2 ALDH1A1 22/4885HSD17B10 788/4885ALOX12 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.