SCHEMBL19785356

SCHEMBL19785356

Clc1cc(C2CCCC2)ccc1-c1ccc(C2CCCC2)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
KCNH2 Q12809 2/20 0.53
CYP2D6 P10635 1/20 0.53
SMURF2 Q9HAU4 1/20 0.42
SMURF1 Q9HCE7 1/20 0.42
ACMSD Q8TDX5 2/20 0.42
PDK2 Q15119 1/20 0.41
BACE1 P56817 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
PRKAB2 O43741 1/20 0.39
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PRKAG3 Q9UGI9 1/20 0.39
PRKAG2 Q9UGJ0 1/20 0.39
PRKAB1 Q9Y478 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15335800 0.84 SLC6A2 (0.70) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL4331978 0.83 SLC6A2 (0.68) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL3785820 0.81 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL2407 0.80 SLC6A2 (0.65) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL3781164 0.79 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL5213516 0.79 ACMSD (0.56) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL3786167 0.79 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL8331330 0.78 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL7458427 0.78 ACMSD (0.57) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL27734625 0.78 SLC6A4 (0.51) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10246415-B2 Process for preparing carbazoles DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-02 US disclosed
WO-2018013067-A1 PROCESS FOR PREPARING CARBAZOLES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246415-B2 Process for preparing carbazoles DCLK2, DCLK1, PDCD2L SLC6A2 3754/4885SLC6A4 4310/4885SLC6A3 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.