Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.68 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15335800 | 0.98 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL2407 | 0.93 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL9870878 | 0.89 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3786167 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3787199 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| Formic Acid SCHEMBL28268519 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL19785356 | 0.83 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3786150 | 0.82 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL8331330 | 0.82 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL19051115 | 0.82 | SLC6A3 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296289-A2 | PHENYL SUBSTITUTED CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sunovion Pharmaceuticals Inc. (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2617704-B1 | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |