Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056277 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL10897063 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL10706838 | 0.79 | MAPT (0.38) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL31366224 | 0.78 | CYP3A4 (0.48) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL10153909 | 0.78 | CYP3A4 (0.48) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL3789309 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL8621100 | 0.76 | APP (0.42) | TERTAPPHPGDMAPTLMNA | |
| SCHEMBL3212678 | 0.76 | HSD17B10 (0.50) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL9322910 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL30016960 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | ALDH1A1 1221/4885TSHR 2754/4885ALOX15 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.