SCHEMBL8621100

SCHEMBL8621100

CN(C)c1ccc(-c2cc(-c3ccc(N(C)C)cc3Cl)cc(-c3ccc(N(C)C)cc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.42
ADK P55263 2/20 0.42
SYK P43405 2/20 0.40
DHODH Q02127 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
PTPN7 P35236 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TERT O14746 1/20 0.38
AURKA O14965 2/20 0.38
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9012579 0.82 SYK (0.41) APPADKSYKMAPTSMN1; SMN2
SCHEMBL8618972 0.79 TOP1 (0.44) LMNAHPGDKMT2AMAPTSMN1; SMN2
SCHEMBL8618775 0.79 MAPT (0.54) APPADKSYKMAPTSMN1; SMN2
SCHEMBL8618905 0.78 APP (0.53) APPSYKHPGDMAPTSMN1; SMN2
SCHEMBL8617979 0.78 APP (0.53) APPSYKHPGDMAPTSMN1; SMN2
SCHEMBL19785366 0.76 ALDH1A1 (0.48) APPDHODHLMNAHPGDPTPN7
SCHEMBL10416337 0.73 CTRC (0.55) APPADKHPGDKMT2AMAPT
SCHEMBL8615693 0.73 PSMB5 (0.49) ADKHPGDKMT2AMAPTSMN1; SMN2
SCHEMBL8616881 0.73 LTB4R (0.55) APPADKSYKLMNAHPGD
SCHEMBL18867181 0.73 ALDH1A1 (0.56) APPSYKHPGDKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
EP-0061128-B1 PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM STERLING DRUG INC. (US) 1985-09-04 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed