SCHEMBL19785401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24125933	0.86	GABRG2 (0.53)	GABRG2GABRB3GABRA5MAP2K4GABRA1
	SCHEMBL16729380	0.83	AKR1C3 (0.45)	GABRG2GABRB3GABRA5MAP2K4GABRA1
	SCHEMBL16729563	0.83	MAP2K4 (0.43)	GABRG2GABRB3GABRA5MAP2K4GABRA1
	SCHEMBL16729385	0.82	AKR1C3 (0.44)	GABRG2GABRB3GABRA5MAP2K4GABRA1
	SCHEMBL20858533	0.78	GABRG2 (0.48)	GABRG2GABRB3GABRA5GABRA1GABRA2
	SCHEMBL10064601	0.78	GABRG2 (0.72)	GABRG2GABRB3GABRA5GABRA1GABRA2
	SCHEMBL409607	0.78	CDK1 (0.54)	GABRG2GABRB3GABRA5GABRA1GABRA2
	SCHEMBL1144957	0.78	GABRG2 (0.51)	GABRG2GABRB3GABRA5GABRA1GABRA2
	SCHEMBL15708456	0.78	MAP2K4 (0.61)	GABRG2GABRB3GABRA5MAP2K4GABRA1
	SCHEMBL31370537	0.78	MAP2K4 (0.47)	GABRG2GABRB3GABRA5MAP2K4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.