Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972300 | 0.84 | HTR6 (0.46) | HTR6L3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL30407382 | 0.84 | HTR6 (0.46) | HTR6L3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL16729466 | 0.82 | MAP2K4 (0.44) | MAP2K4HTR6L3MBTL1MAPTGPR119 | |
| SCHEMBL24067403 | 0.82 | HTR6 (0.46) | HTR6L3MBTL1KRASGABRG2GABRB3 | |
| SCHEMBL12615032 | 0.82 | HTR6 (0.46) | HTR6L3MBTL1KRASGABRG2GABRB3 | |
| SCHEMBL16729405 | 0.81 | MAP2K4 (0.43) | MAP2K4HTR6L3MBTL1MAPTGPR119 | |
| SCHEMBL16727058 | 0.81 | HTR6 (0.52) | MAP2K4HTR6L3MBTL1MAPTGPR119 | |
| SCHEMBL9901232 | 0.81 | HTR6 (0.45) | HTR6L3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL14304582 | 0.81 | AKR1C3 (0.47) | HTR6L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL29942639 | 0.81 | AKR1C3 (0.47) | HTR6L3MBTL1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | MAP2K4 4086/4885HTR6 3245/4885L3MBTL1 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.