Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790081 | 0.88 | CYP11B2 (0.34) | KDM2BPRMT5WDR77DPP4FAP | |
| SCHEMBL1786839 | 0.88 | CYP11B2 (0.34) | KDM2BPRMT5WDR77DPP4FAP | |
| SCHEMBL1791090 | 0.84 | WDR5 (0.34) | KDM2BCYP2D6 | |
| SCHEMBL1788532 | 0.82 | F10 (0.38) | PRMT5WDR77DPP4DPP7 | |
| SCHEMBL1791323 | 0.78 | EPHX2 (0.35) | CYP2D6 | |
| SCHEMBL1977023 | 0.75 | ACACB (0.31) | ACACB | |
| SCHEMBL1789374 | 0.74 | CYP19A1 (0.38) | PRMT5WDR77DPP4 | |
| SCHEMBL1789058 | 0.72 | DPP4 (0.39) | PRMT5WDR77DPP4DPP7 | |
| SCHEMBL1790080 | 0.72 | KDM2B (0.41) | KDM2BPRMT5WDR77CYP2D6 | |
| SCHEMBL1786837 | 0.72 | KDM2B (0.41) | KDM2BPRMT5WDR77CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326625-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |