Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785873 | 0.88 | VEGFA (0.51) | FGFR1VEGFAEGLN1CHRM2CHRM4 | |
| SCHEMBL20150071 | 0.85 | MGLL (0.48) | FGFR1VEGFAEGLN1CHRM2CHRM4 | |
| SCHEMBL4496837 | 0.85 | VEGFA (0.50) | FGFR1VEGFAEGLN1CHRM2CHRM4 | |
| SCHEMBL19785610 | 0.85 | VEGFA (0.42) | FGFR1VEGFAEGLN1CHRM2CHRM4 | |
| SCHEMBL19785782 | 0.83 | MGLL (0.41) | ALDH1A1KDM4EPOLBMGLL | |
| SCHEMBL19785594 | 0.82 | HDAC1 (0.41) | MGLLGPR119 | |
| SCHEMBL29613577 | 0.82 | HDAC1 (0.41) | MGLLGPR119 | |
| SCHEMBL4502120 | 0.80 | VEGFA (0.49) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL13535201 | 0.79 | VEGFA (0.47) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL15265651 | 0.78 | VEGFA (0.47) | VEGFAEGLN1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011201-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |