SCHEMBL19785633

SCHEMBL19785633

Oc1ccc(CSS/C=C\CSc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
BACE1 P56817 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 3/20 0.33
LMNA P02545 2/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
CYP1A2 P05177 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS2 P35354 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HIF1A Q16665 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21189949 0.89 HSD17B10 (0.38) KMT2AMEN1KDM4ENPC1CYP1A2
SCHEMBL21189960 0.89 HSD17B10 (0.38) KMT2AMEN1KDM4ENPC1CYP1A2
SCHEMBL19786064 0.85 ALDH1A1 (0.40) NPC1LMNAALDH1A1RAB9ASMN1; SMN2
SCHEMBL21189914 0.85 MEN1 (0.41) KMT2AMEN1KDM4ENPC1LMNA
SCHEMBL19786067 0.85 HPGD (0.40) KMT2AMEN1KDM4ENPC1ALDH1A1
SCHEMBL19785863 0.85 ALDH1A1 (0.40) NPC1LMNAALDH1A1RAB9ASMN1; SMN2
SCHEMBL21189951 0.85 MEN1 (0.41) KMT2AMEN1KDM4ENPC1LMNA
SCHEMBL19786022 0.85 IDO1 (0.38) IDO1LMNASMN1; SMN2MAPK1
SCHEMBL21190092 0.82 APP (0.44) KMT2AMEN1NPC1LMNAALDH1A1
SCHEMBL21189961 0.82 APP (0.44) KMT2AMEN1NPC1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012947-A1 NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2018-01-18 WO disclosed