Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785863 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAOBMAOALMNA | |
| SCHEMBL21189960 | 0.89 | HSD17B10 (0.38) | ALDH1A1MAOBMAOANPC1RAB9A | |
| SCHEMBL21189949 | 0.89 | HSD17B10 (0.38) | ALDH1A1MAOBMAOANPC1RAB9A | |
| SCHEMBL19786067 | 0.85 | HPGD (0.40) | ALDH1A1SMN1; SMN2MAPTHTTNPC1 | |
| SCHEMBL21189914 | 0.85 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MAOBMAOALMNA | |
| SCHEMBL19785633 | 0.85 | IDO1 (0.36) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL21189951 | 0.85 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MAOBMAOALMNA | |
| SCHEMBL21190121 | 0.84 | LMNA (0.36) | ALDH1A1MAOBLMNAMAPTPKM | |
| SCHEMBL21190098 | 0.84 | LMNA (0.36) | ALDH1A1MAOBLMNAMAPTPKM | |
| SCHEMBL21190022 | 0.82 | APP (0.46) | ALDH1A1SMN1; SMN2MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143142-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOBLASTOMA | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2019143143-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2018012947-A1 | NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | 숙명여자대학교 산학협력단 | 2018-01-18 | — | — | WO | disclosed |