SCHEMBL197857

SCHEMBL197857

CC(=O)Nc1ccnc(-c2cc(NC(C)=O)ccn2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.54
KDM4D Q6B0I6 1/20 0.54
KDM4C Q9H3R0 1/20 0.54
KDM5B Q9UGL1 1/20 0.54
KDM3A Q9Y4C1 1/20 0.54
DYRK1A Q13627 1/20 0.52
KDM4E B2RXH2 6/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
PRNP P04156 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
GRIN2D O15399 1/20 0.51
GRIN3B O60391 1/20 0.51
GRIN1 Q05586 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIN2B Q13224 1/20 0.51
GRIN2C Q14957 1/20 0.51
GRIN3A Q8TCU5 1/20 0.51
MAPT P10636 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5520229 0.82 KDM4E (0.49) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL14168412 0.82 ALDH1A1 (0.52) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL13165570 0.82 TYK2 (0.66) KDM4EMEN1KMT2AGRIN2DGRIN3B
SCHEMBL7672757 0.82 SMARCA2 (0.63) KDM4EMEN1KMT2APRNPPOLB
SCHEMBL26480235 0.81 KDM4E (0.52) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL7672749 0.81 KDM4E (0.47) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL5520232 0.81 JAK2 (0.56) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL21212495 0.81 KDM4E (0.47) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL16305244 0.81 KDM4E (0.47) KDM5AKDM4DKDM4CKDM5BKDM3A
SCHEMBL9687074 0.81 TYK2 (0.49) KDM5AKDM4DKDM4CKDM5BKDM3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
US-20040054267-A1 Small volume in vitro analyte sensor THERASENSE, INC. 2004-03-18 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6591125-B1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. 2003-07-08 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed