SCHEMBL19785872

SCHEMBL19785872

COc1cccc(SC/C=C/SSCc2ccc(C)c(C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MTNR1A P48039 4/20 0.36
MTNR1B P49286 4/20 0.36
MAOB P27338 5/20 0.36
DHFR P00374 1/20 0.36
APP P05067 1/20 0.35
POLB P06746 1/20 0.35
MAOA P21397 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
LTB4R Q15722 1/20 0.34
RIOK2 Q9BVS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19785898 0.88 MAOB (0.46) MTNR1AMTNR1BMAOBDHFRPOLB
SCHEMBL19786014 0.87 APP (0.44) MAOBAPPPOLBMAOARIOK2
SCHEMBL21189911 0.86 MAOB (0.43) MTNR1AMTNR1BMAOBPOLBMAOA
SCHEMBL21189901 0.86 MAOB (0.43) MTNR1AMTNR1BMAOBPOLBMAOA
SCHEMBL21189916 0.85 HRH1 (0.40) ADORA2AADORA1MTNR1AMTNR1BMAOB
SCHEMBL21190021 0.85 HRH1 (0.40) ADORA2AADORA1MTNR1AMTNR1BMAOB
SCHEMBL21190093 0.85 ALDH1A1 (0.39) MTNR1AMTNR1BMAOBMAOACYP1A2
SCHEMBL21189962 0.85 ALDH1A1 (0.39) MTNR1AMTNR1BMAOBMAOACYP1A2
SCHEMBL21190028 0.85 MAOB (0.47) MTNR1AMTNR1BMAOBMAOACYP1A2
SCHEMBL21190019 0.85 MAOB (0.47) MTNR1AMTNR1BMAOBMAOACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012947-A1 NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2018-01-18 WO disclosed