Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 5/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368556 | 1.00 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL29613580 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354252 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL29613557 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354250 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354254 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354290 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354253 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL21354282 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 | |
| Hydrochloric Acid SCHEMBL29613590 | 0.99 | XIAP (0.32) | XIAPBIRC2MLNRCHRM3PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934282-B2 | Heteroaromatic modulators of the retinoid-related orphan receptor gamma | LEO PHARMA A/S (DK) | 2021-03-02 | — | — | US | disclosed |
| US-20200291010-A1 | HETEROAROMATIC MDOULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S | 2020-09-17 | — | — | US | disclosed |
| EP-3484880-B1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA AS (DK) | 2020-09-02 | — | — | EP | disclosed |
| US-10662181-B2 | Heteroaromatic modulators of the retinoid-related orphan receptor gamma | LEO PHARMA A/S (DK) | 2020-05-26 | — | — | US | disclosed |
| US-20190284177-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2019-09-19 | — | — | US | disclosed |
| WO-2018011201-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291010-A1 | HETEROAROMATIC MDOULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | RXRA, RORA, NR1H3 | XIAP 4531/4885BIRC2 4008/4885MLNR 996/4885 |
| US-10934282-B2 | Heteroaromatic modulators of the retinoid-related orphan receptor gamma | RXRA, RXRG, RXRB | XIAP 4037/4885BIRC2 3917/4885MLNR 631/4885 |
| US-10662181-B2 | Heteroaromatic modulators of the retinoid-related orphan receptor gamma | RXRA, RXRG, RXRB | XIAP 4037/4885BIRC2 3917/4885MLNR 631/4885 |
| US-20190284177-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | RXRA, RXRG, RXRB | XIAP 4037/4885BIRC2 3917/4885MLNR 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.