Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977547 | 0.87 | S1PR1 (0.51) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1978561 | 0.87 | S1PR1 (0.51) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1978057 | 0.86 | S1PR5 (0.48) | S1PR1S1PR5S1PR3S1PR4PPARG | |
| SCHEMBL1981574 | 0.84 | SLC6A9 (0.50) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1979472 | 0.81 | S1PR1 (0.47) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1978218 | 0.81 | S1PR5 (0.55) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1981219 | 0.76 | S1PR1 (0.49) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1979473 | 0.76 | S1PR1 (0.42) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1979545 | 0.75 | S1PR1 (0.50) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL1978012 | 0.75 | S1PR1 (0.46) | S1PR1S1PR5S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712618-B | Novel compounds as receptor modulators with therapeutic utility | ALLERGAN INC | 2014-11-26 | — | — | CN | claimed |
| US-8653062-B2 | Compounds as receptor modulators with therapeutic utility | ALLERGAN, INC. (US) | 2014-02-18 | — | — | US | claimed |
| EP-2504328-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | Allergan, Inc. (US) | 2012-10-03 | — | — | EP | claimed |
| CN-102712618-A | Novel compounds as receptor modulators with therapeutic utility | ALLERGAN INC | 2012-10-03 | — | — | CN | claimed |
| US-20110152241-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2011-06-23 | — | — | US | claimed |
| WO-2011066179-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2011-06-03 | — | — | WO | claimed |
| CN-102712618-B | Novel compounds as receptor modulators with therapeutic utility | ALLERGAN INC | 2014-11-26 | — | — | CN | disclosed |
| US-8653062-B2 | Compounds as receptor modulators with therapeutic utility | ALLERGAN, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| EP-2504328-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | Allergan, Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| CN-102712618-A | Novel compounds as receptor modulators with therapeutic utility | ALLERGAN INC | 2012-10-03 | — | — | CN | disclosed |
| US-20110152241-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2011066179-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152241-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | S1PR3, S1PR1, S1PR2 | S1PR1 2/4885S1PR5 4/4885S1PR3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.