SCHEMBL1978626

SCHEMBL1978626

CCCCC(CC)Cn1c2ccc(C(=O)c3ccccc3)cc2c2cc(C(=O)c3ccccc3)ccc21

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.62
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 5/20 0.46
HPGD P15428 2/20 0.46
NPC1 O15118 3/20 0.44
GLA P06280 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR1 P21554 1/20 0.41
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1978510 0.97 CNR2 (0.68) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL13640281 0.94 CNR2 (0.56) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL24494686 0.92 CNR2 (0.61) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL1978488 0.90 CNR2 (0.52) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL25515583 0.87 CNR2 (0.56) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL1980186 0.87 CNR2 (0.47) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL13640229 0.86 CNR2 (0.66) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL22828459 0.86 CNR2 (0.47) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL28946332 0.85 KDM4E (0.54) CNR2KDM4EALDH1A1HPGDNPC1
SCHEMBL23801802 0.84 ALDH1A1 (0.45) CNR2KDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2510400-B1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2015-04-29 EP disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
EP-2510400-A1 UV-LED CURABLE COMPOSITIONS AND INKS Agfa-Gevaert (BE) 2012-10-17 EP disclosed
CN-102640055-A Uv-led curable compositions and inks AGFA GEVAERT 2012-08-15 CN disclosed
WO-2011069943-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed