SCHEMBL1978488

SCHEMBL1978488

CCCCC(CC)Cn1c2ccc(C(=O)C(=O)OCC)cc2c2cc(C(=O)c3ccccc3)ccc21

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.52
ALDH1A1 P00352 7/20 0.40
MAPK1 P28482 3/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 4/20 0.39
HPGD P15428 3/20 0.39
CA2 P00918 1/20 0.38
CYP3A4 P08684 1/20 0.38
SCARB1 Q8WTV0 1/20 0.37
TSHR P16473 2/20 0.37
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12597391 0.92 ALDH1A1 (0.42) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL1979651 0.91 ALDH1A1 (0.47) CNR2ALDH1A1MAPK1KDM4ENPC1
SCHEMBL1978626 0.90 CNR2 (0.62) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL13640281 0.89 CNR2 (0.56) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL18807690 0.88 ALDH1A1 (0.46) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL13640233 0.88 ALDH1A1 (0.39) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL18807691 0.87 ALDH1A1 (0.39) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL12596931 0.87 CNR2 (0.40) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL14212155 0.87 CNR2 (0.45) CNR2ALDH1A1MAPK1LMNAKDM4E
SCHEMBL1978510 0.87 CNR2 (0.68) CNR2ALDH1A1KDM4ENPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2509948-B1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2017-05-03 EP disclosed
EP-2509948-B1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2017-05-03 EP disclosed
EP-2510400-B1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2015-04-29 EP disclosed
EP-2510400-B1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2015-04-29 EP disclosed
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-12-06 US disclosed
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-12-06 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
EP-2510400-A1 UV-LED CURABLE COMPOSITIONS AND INKS Agfa-Gevaert (BE) 2012-10-17 EP disclosed
EP-2509948-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS Agfa-Gevaert (BE) 2012-10-17 EP disclosed
WO-2011069943-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed
WO-2011069947-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed
WO-2011069947-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS WEE1, CBX4, USP9X CNR2 2086/4885ALDH1A1 1029/4885MAPK1 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.