Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580184 | 0.92 | HPGD (0.55) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL16974362 | 0.92 | HPGD (0.55) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL29395325 | 0.88 | HPGD (0.51) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL19362150 | 0.87 | FTO (0.46) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL16745253 | 0.85 | HPGD (0.48) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL31580086 | 0.85 | HPGD (0.48) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL18680082 | 0.84 | CYP3A4 (0.53) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL18685195 | 0.83 | ALDH1A1 (0.55) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL18270247 | 0.81 | CYP3A4 (0.48) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL12056731 | 0.81 | CYP3A4 (0.62) | HPGDALDH1A1CYP3A4TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013999-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | WO | disclosed |