Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19771238 | 0.94 | BRD4 (0.40) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19786886 | 0.92 | MAOA (0.42) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19786883 | 0.89 | KDM4E (0.41) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19786887 | 0.88 | KDM4E (0.41) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19771242 | 0.85 | BRD4 (0.41) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL22099679 | 0.84 | MAOA (0.47) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL22099678 | 0.84 | MAOA (0.47) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19786775 | 0.83 | SMN1; SMN2 (0.48) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL17895236 | 0.82 | ALDH1A1 (0.44) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL19771244 | 0.82 | BRD4 (0.40) | MAOAMAOBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689384-B2 | Imidazo[1,2-a]quinoxalines and derivatives thereof for the treatment of cancer | UNIVERSITE DE MONTPELLIER (FR) | 2020-06-23 | — | — | US | disclosed |
| US-20180016278-A1 | Imidazo[1,2-a]quinoxalines and Derivatives Thereof for the Treatment of Cancer | AXLR, SATT DU LANGUEDOC ROUSSILLON (FR) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689384-B2 | Imidazo[1,2-a]quinoxalines and derivatives thereof for the treatment of cancer | NQO1, NQO2, ABL1 | MAOA 987/4885MAOB 1222/4885KDM4E 918/4885 |
| US-20180016278-A1 | Imidazo[1,2-a]quinoxalines and Derivatives Thereof for the Treatment of Cancer | NQO1, NQO2, ABL1 | MAOA 987/4885MAOB 1222/4885KDM4E 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.