Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666155 | 0.81 | POLB (0.47) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL6177060 | 0.79 | GAA (0.53) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL1532609 | 0.79 | LMNA (0.53) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL128042 | 0.79 | KMT2A (0.58) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL23318140 | 0.78 | ALDH1A1 (0.47) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10518649 | 0.78 | KMT2A (0.47) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL16443965 | 0.78 | ALDH1A1 (0.47) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL3512372 | 0.78 | GAA (0.50) | ALOX15ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL17138144 | 0.76 | ALDH1A1 (0.51) | ALOX15ALDH1A1KMT2ALMNAELANE | |
| SCHEMBL130836 | 0.76 | BCL9 (0.56) | ALOX15ALDH1A1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509978-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E.I. Du Pont De Nemours And Company (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |