Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 8/20 | 0.44 |
| ▸ | FEN1 | P39748 | 8/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716965 | 0.85 | PIK3CD (0.50) | ALOX5APFEN1PIK3CDATRBAZ2B | |
| SCHEMBL19787851 | 0.75 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL21222968 | 0.69 | ALOX5AP (0.55) | ALOX5APFEN1ATRBAZ2BBAZ2A | |
| SCHEMBL2717234 | 0.69 | PIK3CD (0.43) | ALOX5APFEN1PIK3CDBAZ2BBAZ2A | |
| SCHEMBL2719860 | 0.69 | PIK3CD (0.44) | ALOX5APFEN1PIK3CDBAZ2BBAZ2A | |
| Hydrochloric Acid SCHEMBL23646294 | 0.68 | ALOX5AP (0.53) | ALOX5APFEN1ATRBAZ2BBAZ2A | |
| SCHEMBL5831677 | 0.68 | ALOX5AP (0.48) | ALOX5APFEN1BAZ2BBAZ2AHSD11B1 | |
| SCHEMBL5723501 | 0.68 | ALOX5AP (0.49) | ALOX5APFEN1PIK3CDATRBAZ2B | |
| SCHEMBL2719477 | 0.68 | PIK3CD (0.42) | ALOX5APFEN1PIK3CDBAZ2BBAZ2A | |
| SCHEMBL18233525 | 0.68 | PIK3CD (0.42) | ALOX5APFEN1PIK3CDBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873704-B2 | Heterocyclic compounds and their uses | AMGEN INC. (US) | 2018-01-23 | — | — | US | disclosed |