Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.49 |
| ▸ | FEN1 | P39748 | 5/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061390 | 0.83 | ADRA2A (0.38) | ALOX5APFEN1ACLYPTGES2 | |
| SCHEMBL5831677 | 0.83 | ALOX5AP (0.48) | ALOX5APFEN1BAZ2BBAZ2ABRD9 | |
| SCHEMBL6308004 | 0.80 | ALOX5AP (0.56) | ALOX5APFEN1 | |
| SCHEMBL2716965 | 0.75 | PIK3CD (0.50) | ALOX5APFEN1BAZ2BBAZ2ABRD9 | |
| SCHEMBL514170 | 0.75 | ALDH1A1 (0.44) | HSD11B1ACLYALDH1A1KMT2A | |
| SCHEMBL15051995 | 0.75 | ALDH1A1 (0.45) | ALOX5APFEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL6820364 | 0.74 | CA2 (0.50) | ALOX5APFEN1BAZ2BBAZ2ABRD9 | |
| SCHEMBL3828691 | 0.72 | ALOX5AP (0.61) | ALOX5APFEN1 | |
| SCHEMBL9538025 | 0.71 | PTGS2 (0.52) | ALOX5APFEN1ACLYPTGS2ATR | |
| SCHEMBL3790468 | 0.71 | ALDH1A1 (0.59) | ALOX5APFEN1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-B1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER LAMBERT CO (US) | 2006-03-15 | — | — | EP | disclosed |