Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23513617 | 0.83 | SIRT1 (0.40) | SMN1; SMN2FOLH1ALDH1A1KDM4EALB | |
| SCHEMBL2735591 | 0.82 | FOLH1 (0.71) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL18377220 | 0.82 | FOLH1 (0.40) | SMN1; SMN2FOLH1ALDH1A1KDM4ENOD1 | |
| SCHEMBL21673279 | 0.82 | FOLH1 (0.54) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL13262513 | 0.82 | FOLH1 (0.40) | SMN1; SMN2FOLH1ALDH1A1KDM4ENOD1 | |
| SCHEMBL13595628 | 0.82 | FOLH1 (0.54) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL1200060 | 0.82 | FOLH1 (0.71) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL16393150 | 0.82 | FOLH1 (0.71) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL20682458 | 0.82 | SIRT6 (0.40) | SMN1; SMN2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL15160689 | 0.82 | NOD1 (0.44) | SMN1; SMN2FOLH1ALDH1A1GNPATNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347785-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2021-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347785-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | CD274, PDCD1, PDCD1LG2 | SMN1; SMN2 4470/4885FOLH1 3407/4885ALDH1A1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.