Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17603099 | 0.79 | DUT (0.36) | — | |
| SCHEMBL31708156 | 0.78 | KMT2A (0.49) | KMT2AFDPSLMNAALDH1A1 | |
| SCHEMBL15193512 | 0.78 | KMT2A (0.49) | KMT2AFDPSLMNAALDH1A1 | |
| SCHEMBL14459652 | 0.76 | KMT2A (0.36) | KMT2AFDPSLMNAADORA2BFPR2 | |
| SCHEMBL26196835 | 0.73 | KDR (0.32) | KMT2AFDPSFPR2ALDH1A1POLB | |
| SCHEMBL440676 | 0.66 | — | — | |
| SCHEMBL9421338 | 0.66 | ESR1 (0.44) | KMT2AFDPSLMNAADORA2BFPR2 | |
| Hydrochloric Acid SCHEMBL15436961 | 0.65 | KMT2A (0.60) | KMT2AFDPSLMNAALDH1A1POLB | |
| SCHEMBL28640086 | 0.64 | — | — | |
| SCHEMBL17544816 | 0.64 | KMT2A (0.43) | KMT2AFDPSLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873680-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2018-01-23 | — | — | US | disclosed |