Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26196835 | 0.77 | KDR (0.32) | KMT2AALDH1A1POLBTLR8FPR2 | |
| SCHEMBL13946295 | 0.76 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8FDPS | |
| SCHEMBL19788985 | 0.76 | KMT2A (0.33) | KMT2AALDH1A1POLBFPR2FDPS | |
| SCHEMBL18912333 | 0.71 | KMT2A (0.42) | KMT2AALDH1A1POLBTLR8ADORA2B | |
| SCHEMBL18905838 | 0.71 | KMT2A (0.44) | KMT2AALDH1A1POLBTLR8ADORA2B | |
| SCHEMBL26196840 | 0.71 | ALPG (0.48) | KMT2AALDH1A1POLBTLR8FPR2 | |
| SCHEMBL440676 | 0.70 | — | — | |
| SCHEMBL9421338 | 0.69 | ESR1 (0.44) | KMT2AALDH1A1POLBTLR8FPR2 | |
| Hydrochloric Acid SCHEMBL15436961 | 0.68 | KMT2A (0.60) | KMT2AALDH1A1POLBFDPSLMNA | |
| SCHEMBL11295344 | 0.68 | KCNH2 (0.42) | KMT2AALDH1A1POLBTLR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244738-B2 | Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists | ROCHE PALO ALTO LLC (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244738-B2 | Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists | ROCHE PALO ALTO LLC (US) | 2007-07-17 | — | — | US | disclosed |