SCHEMBL19789045

SCHEMBL19789045

CC/C=C(\SCc1ccccc1)c1cccc(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.47
GPR52 Q9Y2T5 1/20 0.43
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 3/20 0.38
HPGD P15428 2/20 0.38
VNN1 O95497 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15215286 0.76 RAB9A (0.52) TAAR1GPR52RAB9ANPC1SMN1; SMN2
SCHEMBL6547170 0.73 SMN1; SMN2 (0.46) GPR52RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL7641156 0.73 HPGD (0.47) GPR52RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL22931047 0.71 HDAC3 (0.42) RAB9ANPC1SMN1; SMN2HDAC3HDAC4
SCHEMBL9226012 0.69 IDO1 (0.50) TAAR1SMN1; SMN2L3MBTL1TDP1POLB
SCHEMBL9226016 0.69 IDO1 (0.50) TAAR1SMN1; SMN2L3MBTL1TDP1POLB
SCHEMBL19156896 0.68 PARP1 (0.53) GPR52RAB9ASMN1; SMN2L3MBTL1TDP1
SCHEMBL11846947 0.68 RAB9A (0.52) GPR52RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL28224464 0.68 GPR52 (0.48) GPR52RAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL7517945 0.66 IDO1 (0.44) TAAR1L3MBTL1TDP1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2725080-B1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2018-01-24 EP disclosed