SCHEMBL19789499

SCHEMBL19789499

[SiH3]c1ccccc1ONOc1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
KCNA3 P22001 2/20 0.33
LTA4H P09960 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.33
HTR1A P08908 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
DRD2 P14416 3/20 0.31
DRD4 P21917 3/20 0.31
DRD3 P35462 2/20 0.31
HTR1B P28222 2/20 0.31
HTR1D P28221 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CA4 P22748 1/20 0.31
ALPL P05186 1/20 0.31
ALPI P09923 1/20 0.31
ALPG P10696 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790430 0.79 LTA4H (0.50) TSHRKCNA3LTA4HL3MBTL1DRD2
SCHEMBL2121426 0.77 LTA4H (0.47) TSHRKCNA3LTA4HL3MBTL1DRD2
SCHEMBL21328562 0.77 LTA4H (0.47) TSHRKCNA3LTA4HL3MBTL1DRD2
Hydrochloric Acid SCHEMBL29091986 0.77 LTA4H (0.47) TSHRKCNA3LTA4HDRD2DRD4
SCHEMBL1929896 0.73 LTA4H (0.52) TSHRLTA4HL3MBTL1HTR1AKMT2A
SCHEMBL18096766 0.70 TSHR (0.48) TSHRLTA4HL3MBTL1HTR1AKMT2A
SCHEMBL28558218 0.70 TSHR (0.48) TSHRLTA4HL3MBTL1HTR1AKMT2A
SCHEMBL22200427 0.66 CA4 (0.50) TSHRKCNA3LTA4HDRD2DRD4
SCHEMBL10859093 0.65 KDM4E (0.39) L3MBTL1ALOX15ALPLALPIALPG
SCHEMBL29092781 0.65 PGR (0.46) TSHRMEN1KMT2ACA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3272844-A1 VISCOSITY INDEX IMPROVER, LUBRICANT COMPOSITION AND METHOD FOR PRODUCING LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2018-01-24 EP disclosed