Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789699 | 0.87 | HTR1D (0.38) | HTR1DHTR1BNPC1ALDH1A1HTT | |
| SCHEMBL26464010 | 0.82 | SLC10A2 (0.39) | SLC10A2 | |
| SCHEMBL19789866 | 0.68 | SLC10A2 (0.42) | SLC10A2CA1CA2 | |
| SCHEMBL19789732 | 0.68 | SLC10A2 (0.41) | SLC10A2TP53POLBMAPTCA1 | |
| SCHEMBL19789796 | 0.68 | SLC10A2 (0.41) | SLC10A2TP53POLBMAPTCA1 | |
| SCHEMBL13620465 | 0.68 | SLC10A2 (0.42) | SLC10A2 | |
| SCHEMBL29684900 | 0.66 | GRM2 (0.38) | CHRM5CHRM1CHRM3SLC10A2 | |
| SCHEMBL9827706 | 0.65 | SRD5A1 (0.39) | HTR1DHTR1BCHRM5CHRM1CHRM3 | |
| SCHEMBL14526553 | 0.64 | HTR1D (0.49) | HTR1DHTR1BCHRM5CHRM1CHRM3 | |
| SCHEMBL6160107 | 0.63 | HTR1D (0.55) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |