SCHEMBL19789732

SCHEMBL19789732

CCCCC1C[C@H](c2cccc(N)c2)c2cc(F)ccc2S(=O)(=O)C1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 15/20 0.41
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19789796 1.00 SLC10A2 (0.41) SLC10A2CA1CA2CA9TP53
SCHEMBL19789755 0.90 SLC10A2 (0.37) SLC10A2CA1CA2PTGDR2
SCHEMBL19789865 0.86 SLC10A2 (0.56) SLC10A2
SCHEMBL19789664 0.79 SLC10A2 (0.40) SLC10A2CA1CA2CA9
SCHEMBL19789679 0.76
SCHEMBL19789673 0.76 SLC10A2 (0.49) SLC10A2
SCHEMBL25060233 0.74 SLC10A2 (0.52) SLC10A2
SCHEMBL19789702 0.73 SLC10A2 (0.44) SLC10A2
SCHEMBL28792538 0.73 SLC10A2 (0.39) SLC10A2CA1CA2CA9TP53
SCHEMBL19789811 0.72 SLC10A2 (0.46) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2282991-B1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI AVENTIS DEUTSCHLAND (DE) 2018-01-24 EP disclosed