Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 9/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620064 | 1.00 | SLC10A2 (0.44) | SLC10A2NPSR1ALDH1A1PKMCACNA1C | |
| SCHEMBL19789811 | 0.84 | SLC10A2 (0.46) | SLC10A2 | |
| SCHEMBL13620066 | 0.84 | SLC10A2 (0.46) | SLC10A2 | |
| SCHEMBL19789694 | 0.82 | ADRA1D (0.38) | SLC10A2 | |
| SCHEMBL348852 | 0.79 | SLC10A2 (0.62) | SLC10A2 | |
| SCHEMBL12196580 | 0.77 | SLC10A2 (0.64) | SLC10A2 | |
| SCHEMBL12196417 | 0.77 | SLC10A2 (0.64) | SLC10A2 | |
| SCHEMBL12196419 | 0.77 | SLC10A2 (0.64) | SLC10A2 | |
| SCHEMBL12196415 | 0.77 | SLC10A2 (0.64) | SLC10A2 | |
| SCHEMBL12196421 | 0.77 | SLC10A2 (0.64) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |