⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311876 | 0.85 | ALDH1A1 (0.53) | — | |
| SCHEMBL2706963 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL4645775 | 0.79 | ALDH1A1 (0.42) | — | |
| SCHEMBL10950285 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL12814201 | 0.78 | — | — | |
| SCHEMBL6572365 | 0.78 | — | — | |
| SCHEMBL713608 | 0.78 | — | — | |
| SCHEMBL10457016 | 0.77 | — | — | |
| SCHEMBL11625780 | 0.77 | NPC1 (0.38) | — | |
| SCHEMBL28131182 | 0.77 | NAAA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037338-B2 | Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2024-07-16 | — | — | US | claimed |
| US-20210300933-A1 | IMIDAZOPYRIMIDINE AND IMIDAZOTRIAZINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2021-09-30 | — | — | US | claimed |
| JP-2193943-A | — | — | None | — | — | JP | disclosed |
| US-20250084044-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| EP-4462999-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| US-20240352023-A1 | IMIDAZOPYRIMIDINE AND IMIDAZOTRIAZINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2024-10-24 | — | — | US | disclosed |
| WO-2024182788-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| CN-118541030-A | Protoporphyrinogen oxidase inhibitors | 恩科化学公司 | 2024-08-23 | — | — | CN | disclosed |
| US-12037338-B2 | Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2024-07-16 | — | — | US | disclosed |
| CN-117164418-B | Alpha-halogenated ketone, efficient synthesis method and application thereof | 徐州医科大学 | 2024-07-02 | — | — | CN | disclosed |
| US-11912860-B2 | Highly loaded inorganic filled organic resin systems | CORNING INCORPORATED (US) | 2024-02-27 | — | — | US | disclosed |
| US-4271167-A | ANTHELMINTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-06-02 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4168169-A | SUBSTITUTED THIAZOLINE, OXAZOLINE, OR IMIDAZOLINE SILVER HALIDE COMPLEXING AGENT | EASTMAN KODAK COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4150223-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4099000-A | PROCESS FOR PREPARING DI-7-AZIDO CEPHALOSPORIN COMPOUNDS | MERCK & CO., INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4079179-A | 6-Loweralkoxy or loweralkylthio-3-cephem-4-carboxylic acids | MERCK & CO., INC. (US) | 1978-03-14 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |