SCHEMBL19789664

SCHEMBL19789664

CCCCC1CS(=O)(=O)c2ccc(F)cc2[C@@H](c2cccc(N)c2)O1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 14/20 0.40
GRM2 Q14416 3/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19789732 0.79 SLC10A2 (0.41) SLC10A2CA1CA2CA9
SCHEMBL19789796 0.79 SLC10A2 (0.41) SLC10A2CA1CA2CA9
SCHEMBL19789755 0.72 SLC10A2 (0.37) SLC10A2CA1CA2
SCHEMBL19789811 0.71 SLC10A2 (0.46) SLC10A2
SCHEMBL13620066 0.71 SLC10A2 (0.46) SLC10A2
SCHEMBL19789673 0.69 SLC10A2 (0.49) SLC10A2
SCHEMBL12196422 0.69 SLC10A2 (0.75) SLC10A2
SCHEMBL12196425 0.69 SLC10A2 (0.75) SLC10A2
SCHEMBL12196428 0.69 SLC10A2 (0.75) SLC10A2
SCHEMBL12196426 0.69 SLC10A2 (0.75) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2282991-B1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI AVENTIS DEUTSCHLAND (DE) 2018-01-24 EP disclosed