SCHEMBL19789737

SCHEMBL19789737

CCCC[C@@]1(CC)CCc2cc(N(C)C)ccc2S(=O)(=O)C1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13620465 0.83 SLC10A2 (0.42) SLC10A2
SCHEMBL24220258 0.78 SLC10A2 (0.41) SLC10A2
SCHEMBL26464062 0.77 SLC10A2 (0.37) SLC10A2
SCHEMBL22360158 0.76 SLC10A2 (0.37) SLC10A2
SCHEMBL19789663 0.75 ALDH1A1 (0.32) SLC10A2
SCHEMBL27307385 0.74 SLC10A2 (0.56) SLC10A2
SCHEMBL30917899 0.74 SLC10A2 (0.62) SLC10A2
SCHEMBL13044311 0.74 SLC10A2 (0.62) SLC10A2
SCHEMBL16068133 0.74 SLC10A2 (0.60) SLC10A2
SCHEMBL18750559 0.73 SLC10A2 (0.63) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3278796-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF HYPERCHOLEMIA AND CHOLESTATIC LIVER DISEASE Lumena Pharmaceuticals LLC (US) 2018-02-07 EP disclosed
EP-2282991-B1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI AVENTIS DEUTSCHLAND (DE) 2018-01-24 EP disclosed