Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547575 | 0.78 | MEN1 (0.61) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL10547979 | 0.78 | MEN1 (0.56) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL10547343 | 0.76 | MEN1 (0.54) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL8672719 | 0.76 | MEN1 (0.58) | MEN1KMT2ADHODHESR1ESR2 | |
| SCHEMBL13172436 | 0.76 | MEN1 (0.58) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL12970468 | 0.75 | MEN1 (0.53) | MEN1KMT2ADHODHESR1ESR2 | |
| SCHEMBL13173702 | 0.75 | MEN1 (0.53) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL8407200 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2ADHODHESR2MAPT | |
| SCHEMBL10548598 | 0.75 | MEN1 (0.53) | MEN1KMT2ADHODHPIK3CGMAPT | |
| SCHEMBL28037618 | 0.74 | KMT2A (0.71) | MEN1KMT2ADHODHMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393787-B1 | CADHERIN-11 INHIBITORS AND METHODS OF USE THEREOF | UNIV GEORGETOWN (US) | 2018-01-24 | — | — | EP | disclosed |