Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789792 | 0.84 | MEN1 (0.41) | IGFBP3LMNAMAPT | |
| SCHEMBL13620099 | 0.70 | CES2 (0.47) | MAPT | |
| SCHEMBL13620292 | 0.69 | DDR1 (0.31) | — | |
| SCHEMBL12221802 | 0.69 | DDR1 (0.31) | — | |
| SCHEMBL19789740 | 0.68 | MAPK14 (0.36) | LMNACNR2 | |
| SCHEMBL13620463 | 0.66 | MEN1 (0.39) | LMNAMAPTTSHR | |
| SCHEMBL19789724 | 0.66 | MEN1 (0.39) | LMNAMAPTTSHR | |
| SCHEMBL24556720 | 0.62 | MAPT (0.64) | LMNAMAPTTSHR | |
| SCHEMBL15636197 | 0.60 | KDM6B (0.54) | CNR2 | |
| SCHEMBL27352538 | 0.60 | PLK1 (0.52) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |