Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19339716 | 0.91 | TRPV1 (0.40) | SSTR3PDE10ASCN10ASCN5A | |
| SCHEMBL13758819 | 0.88 | SCN10A (0.41) | SCN10ASCN5AKLK1KLK5 | |
| SCHEMBL18526452 | 0.87 | SCN10A (0.40) | SSTR3PDE10ASCN10ASCN5AKLK1 | |
| SCHEMBL18526771 | 0.86 | PDE10A (0.46) | SSTR3PDE10A | |
| SCHEMBL16133430 | 0.84 | HPGDS (0.43) | SSTR3PDE10ASCN10ASCN5AKLK1 | |
| SCHEMBL18526728 | 0.84 | SCN10A (0.38) | SSTR3PDE10ASCN10ASCN5AKLK1 | |
| SCHEMBL19339625 | 0.83 | LIMK1 (0.34) | SSTR3PDE10ASCN10ASCN5AKLK1 | |
| SCHEMBL19339623 | 0.82 | LPL (0.41) | SSTR3PDE10A | |
| SCHEMBL20221011 | 0.81 | SSTR3 (0.36) | SSTR3SCN10A | |
| SCHEMBL11982065 | 0.81 | SSTR3 (0.36) | SSTR3SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321263-A2 | COMPOUNDS FOR PREPARING HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Holdings Ireland (CH) | 2018-05-16 | — | — | EP | disclosed |
| EP-3042901-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB HOLDINGS IRELAND (CH) | 2018-01-24 | — | — | EP | disclosed |