Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23513631 | 0.88 | CYP2C19 (0.60) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL19483469 | 0.86 | RAB9A (0.51) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL14010003 | 0.86 | RAB9A (0.51) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL15185809 | 0.85 | RAB9A (0.50) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL14048129 | 0.84 | CYP2C19 (0.54) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL8301760 | 0.84 | CYP2C19 (0.54) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL12220083 | 0.84 | CYP2C19 (0.54) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL15075357 | 0.83 | CYP2C19 (0.53) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL25721680 | 0.83 | RAB9A (0.54) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA | |
| SCHEMBL5831753 | 0.80 | CYP2C19 (0.61) | RAB9ACYP2C19NPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794634-B1 | PROCESS FOR THE SYNTHESIS OF GHRELIN ANALOGUES | IPSEN MFG IRELAND LIMITED (IE) | 2018-01-24 | — | — | EP | disclosed |